Bora manufactures Prescription (Rx) and Over-the Counter (OTC) nasal sprays
Nasal sprays are a great way to deliver drugs to mucosal membranes and potentially the Central Nervous System. Many of these are packaged in a delivery device that makes them a drug device combination product. Additionally, drug manufacturers must overcome several technical and analytical challenges before they can safely bring their nasal formulations to patients.
Comprehensive services to expedite your nasal spray to market
We offer high-speed and high-throughput manufacturing of nasal sprays including sprays with challenging APIs such as steroids and high-potency APIs. Our air quality for manufacturing and filling meets ISO Class 7 standards.
Best-in-class analytical and specialty testing
Bora Pharmaceutical offers extensive analytical testing services for nasal sprays.
- Process and cleaning validation
- Particle and droplet size analysis
- Stability studies
- Finished product and impurities testing
Nasal Spray Manufacturing Process Overview
This video demonstrates Bora Pharmaceuticals' nasal spray packaging and liquid filling process at our state-of-the-art manufacturing facility. The production line showcases our automated filling equipment precisely dispensing metered-dose nasal spray formulations into individual containers.
Full Video Transcript
The video begins with an overview of Bora's nasal spray packaging line. Automated machinery fills each nasal spray unit with a precisely metered dose of liquid formulation. Quality control checkpoints are integrated throughout the line to verify fill volumes and container integrity. Finished nasal spray units move through serialization and secondary packaging stations before being prepared for distribution. Bora's GMP-compliant process ensures consistent product quality from formulation through final packaged product.
State-of-the-art manufacturing, filling, packaging, and serialization
At our world-class Mississauga, Canada facility, we have a dedicated manufacturing area and high-speed line for nasal sprays fitted with fully automated Groninger filling machines and crimping heads.
The facility can produce around 170 bottles per minute and has a total capacity of 29 million bottles per year. We offer glass filling for nasal sprays with crimp and screw-on pumps, complete with packaging, labeling, and serialization. Our cleanrooms for manufacturing and filling nasal sprays meet ISO Class 7 air quality.
