{"id":497,"date":"2021-09-16T06:44:20","date_gmt":"2021-09-16T06:44:20","guid":{"rendered":"http:\/\/boracdmo.com\/?page_id=497"},"modified":"2026-05-14T17:30:01","modified_gmt":"2026-05-14T17:30:01","slug":"formulation-development","status":"publish","type":"page","link":"https:\/\/boracdmo.com\/formulation-development\/","title":{"rendered":"Formulation Development"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"497\" class=\"elementor elementor-497\" data-elementor-post-type=\"page\">\n\t\t\t\t<div class=\"elementor-element elementor-element-c05ead0 e-flex e-con-boxed e-con e-parent\" data-id=\"c05ead0\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-110ca8a elementor-widget elementor-widget-heading\" data-id=\"110ca8a\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Find the flexibility your formulation needs<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-be268d5 elementor-widget elementor-widget-text-editor\" data-id=\"be268d5\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<div class=\"formulation-dosing-content\"><p>We are proud to help our partners\u2019 innovations reach patients faster by accelerating program agility earlier in development.<\/p><\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-6568af1 elementor-widget elementor-widget-text-editor\" data-id=\"6568af1\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<div class=\"formulation-dosing-content\">\n\nBora\u2019s formulation development teams have experience supporting commercial development and manufacturing strategies across a wide range of drug programs.\n\n<\/div>\n<div class=\"formulation-dosing-content\">\n\nWith a specialized focus on oral solid dose (OSD) drug substance and finished drug products, Bora delivers robust formulation expertise that can help accelerate New Drug Approval (NDA), Amended New Drug Approval (ANDA) and 505(b)(2) programs through all phases of development and commercial launch.\n\n<\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-22c8ad7 e-flex e-con-boxed e-con e-parent\" data-id=\"22c8ad7\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;gradient&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-f321be1 elementor-widget elementor-widget-heading\" data-id=\"f321be1\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Flexibility for a faster timeline\n<\/h2>\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-ea74ae2 e-con-full e-flex e-con e-child\" data-id=\"ea74ae2\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-b9a2031 e-con-full e-flex e-con e-child\" data-id=\"b9a2031\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-30dcc66 elementor-widget elementor-widget-image\" data-id=\"30dcc66\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"660\" height=\"441\" src=\"https:\/\/boracdmo.com\/wp-content\/uploads\/sites\/2\/2021\/10\/0117-qc-disintegration-pharmatron-dt50.jpg\" class=\"attachment-large size-large wp-image-1647\" alt=\"Pharmatron DT50 disintegration tester used in pharmaceutical QC during formulation development.\" srcset=\"https:\/\/boracdmo.com\/wp-content\/uploads\/sites\/2\/2021\/10\/0117-qc-disintegration-pharmatron-dt50.jpg 660w, https:\/\/boracdmo.com\/wp-content\/uploads\/sites\/2\/2021\/10\/0117-qc-disintegration-pharmatron-dt50-300x200.jpg 300w, https:\/\/boracdmo.com\/wp-content\/uploads\/sites\/2\/2021\/10\/0117-qc-disintegration-pharmatron-dt50-480x321.jpg 480w\" sizes=\"(max-width: 660px) 100vw, 660px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-e55d75e e-con-full e-flex e-con e-child\" data-id=\"e55d75e\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-7c7e28b elementor-widget elementor-widget-text-editor\" data-id=\"7c7e28b\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>Our development teams focus on shortening project timelines through several high-performance evaluations that are designed to engineer the desired formulation characteristics to be technically transferred and scalable throughout the drug\u2019s life cycle. These services include:<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-3d84701 elementor-icon-list--layout-traditional elementor-list-item-link-full_width elementor-widget elementor-widget-icon-list\" data-id=\"3d84701\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"icon-list.default\">\n\t\t\t\t\t\t\t<ul class=\"elementor-icon-list-items\">\n\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-square-full\" viewBox=\"0 0 512 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M512 512H0V0h512v512z\"><\/path><\/svg>\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">Pre-formulation<\/span>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-square-full\" viewBox=\"0 0 512 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M512 512H0V0h512v512z\"><\/path><\/svg>\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">Excipient and API compatibility assessment<\/span>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-square-full\" viewBox=\"0 0 512 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M512 512H0V0h512v512z\"><\/path><\/svg>\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">Physicochemical testing<\/span>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-square-full\" viewBox=\"0 0 512 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M512 512H0V0h512v512z\"><\/path><\/svg>\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">Formulation screening<\/span>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-square-full\" viewBox=\"0 0 512 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M512 512H0V0h512v512z\"><\/path><\/svg>\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">Formulation scale-up and accelerated stability studies<\/span>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t<\/ul>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-ae5c4a2 e-flex e-con-boxed e-con e-parent\" data-id=\"ae5c4a2\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-529ed36 e-con-full e-flex e-con e-child\" data-id=\"529ed36\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-c52e07c e-con-full card e-flex e-con e-child\" data-id=\"c52e07c\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-32ef796 elementor-widget elementor-widget-heading\" data-id=\"32ef796\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Scale-up and cGMP drug substance manufacturing\n<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-02a99ec elementor-widget elementor-widget-text-editor\" data-id=\"02a99ec\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<div class=\"formulation-scaleup-content\">\n\nA robust formulation is the key to sustained commercial success along with new formulations to extend the product lifecycle. To assure better program outcomes, Bora\u2019s formulation development teams understand how to leverage raw materials, excipients, and manufacturing processes to create robust, efficient formulations. These can support the economical scale up during the different clinical phases through to commercial and the technical transfer of the formulation to subsequent manufacturing sites (if necessary).\n<\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-ac3c1d9 e-con-full e-flex e-con e-child\" data-id=\"ac3c1d9\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-ec59fa0 elementor-widget elementor-widget-image\" data-id=\"ec59fa0\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"650\" height=\"400\" src=\"https:\/\/boracdmo.com\/wp-content\/uploads\/sites\/2\/2022\/04\/Packaging-and-Serialization.png\" class=\"attachment-large size-large wp-image-245046\" alt=\"Bora packaging and serialization line with operators inspecting cartons on automated conveyor system.\" srcset=\"https:\/\/boracdmo.com\/wp-content\/uploads\/sites\/2\/2022\/04\/Packaging-and-Serialization.png 650w, https:\/\/boracdmo.com\/wp-content\/uploads\/sites\/2\/2022\/04\/Packaging-and-Serialization-300x185.png 300w, https:\/\/boracdmo.com\/wp-content\/uploads\/sites\/2\/2022\/04\/Packaging-and-Serialization-480x295.png 480w\" sizes=\"(max-width: 650px) 100vw, 650px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-ec772ed e-flex e-con-boxed e-con e-parent\" data-id=\"ec772ed\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;gradient&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-bf4abb8 e-con-full e-flex e-con e-child\" data-id=\"bf4abb8\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-b4633b4 elementor-widget elementor-widget-image\" data-id=\"b4633b4\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"650\" height=\"400\" src=\"https:\/\/boracdmo.com\/wp-content\/uploads\/sites\/2\/2022\/04\/Liquids.png\" class=\"attachment-large size-large wp-image-244973\" alt=\"Liquid pharmaceutical formulation development for oral and topical dosage forms at Bora CDMO.\" srcset=\"https:\/\/boracdmo.com\/wp-content\/uploads\/sites\/2\/2022\/04\/Liquids.png 650w, https:\/\/boracdmo.com\/wp-content\/uploads\/sites\/2\/2022\/04\/Liquids-300x185.png 300w, https:\/\/boracdmo.com\/wp-content\/uploads\/sites\/2\/2022\/04\/Liquids-480x295.png 480w\" sizes=\"(max-width: 650px) 100vw, 650px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-2a3fc9d e-con-full e-flex e-con e-child\" data-id=\"2a3fc9d\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-0f07121 elementor-widget elementor-widget-heading\" data-id=\"0f07121\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Dosing and delivery strategies\n<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-a4d9f11 elementor-widget elementor-widget-text-editor\" data-id=\"a4d9f11\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>Robust formulation chemistries also prepare the drug substance for advanced dosing and delivery strategies. From solving bioavailability and solubility issues, getting actives past the upper GI tract, or combining APls for patient compliance reasons, Bora offers advanced formulation strategies and delivery technologies including:<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-363f1d7 elementor-icon-list--layout-traditional elementor-list-item-link-full_width elementor-widget elementor-widget-icon-list\" data-id=\"363f1d7\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"icon-list.default\">\n\t\t\t\t\t\t\t<ul class=\"elementor-icon-list-items\">\n\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-square-full\" viewBox=\"0 0 512 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M512 512H0V0h512v512z\"><\/path><\/svg>\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">Amorphous particles and coated pellets<\/span>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-square-full\" viewBox=\"0 0 512 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M512 512H0V0h512v512z\"><\/path><\/svg>\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">Multi-unit particle systems (MUPS)<\/span>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-square-full\" viewBox=\"0 0 512 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M512 512H0V0h512v512z\"><\/path><\/svg>\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">Tablets \u2013 enteric coated, matrix, bi-layered and miniature forms<\/span>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-square-full\" viewBox=\"0 0 512 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M512 512H0V0h512v512z\"><\/path><\/svg>\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">Capsules \u2013 single and combination fills: powders, pellets, tablets, micro-tablets<\/span>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-square-full\" viewBox=\"0 0 512 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M512 512H0V0h512v512z\"><\/path><\/svg>\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">Semi-solid \u2013 scale up equipment 2.5Kg to 125Kg, small scale tube filing<\/span>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-square-full\" viewBox=\"0 0 512 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M512 512H0V0h512v512z\"><\/path><\/svg>\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">Liquid- small scale 10L to 600L scale and semi manual small scale bottle filling<\/span>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t<\/ul>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Find the flexibility your formulation needs We are proud to help our partners\u2019 innovations reach patients faster by accelerating program agility earlier in development. Bora\u2019s formulation development teams have experience supporting commercial development and manufacturing strategies across a wide range of drug programs. With a specialized focus on oral solid dose (OSD) drug substance and [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"parent":0,"menu_order":11,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"content-type":"","_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"class_list":["post-497","page","type-page","status-publish","hentry"],"aioseo_notices":[],"acf":[],"_links":{"self":[{"href":"https:\/\/boracdmo.com\/en\/wp-json\/wp\/v2\/pages\/497","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/boracdmo.com\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/boracdmo.com\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/boracdmo.com\/en\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/boracdmo.com\/en\/wp-json\/wp\/v2\/comments?post=497"}],"version-history":[{"count":46,"href":"https:\/\/boracdmo.com\/en\/wp-json\/wp\/v2\/pages\/497\/revisions"}],"predecessor-version":[{"id":987502788,"href":"https:\/\/boracdmo.com\/en\/wp-json\/wp\/v2\/pages\/497\/revisions\/987502788"}],"wp:attachment":[{"href":"https:\/\/boracdmo.com\/en\/wp-json\/wp\/v2\/media?parent=497"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}