{"id":248468,"date":"2023-04-11T17:13:07","date_gmt":"2023-04-11T21:13:07","guid":{"rendered":"http:\/\/boracdmo.com\/?page_id=248468"},"modified":"2026-05-15T13:07:52","modified_gmt":"2026-05-15T13:07:52","slug":"ophthalmic","status":"publish","type":"page","link":"https:\/\/boracdmo.com\/ophthalmic\/","title":{"rendered":"Ophthalmic CDMO Manufacturing Services"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"248468\" class=\"elementor elementor-248468\" data-elementor-post-type=\"page\">\n\t\t\t\t<div class=\"elementor-element elementor-element-d196f29 e-flex e-con-boxed e-con e-parent\" data-id=\"d196f29\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-f4fbc7d elementor-widget elementor-widget-heading\" data-id=\"f4fbc7d\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Commercial ophthalmic manufacturing<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-f8754c5 elementor-widget elementor-widget-text-editor\" data-id=\"f8754c5\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>\u200bThe known advantages of the ocular route of drug administration is that it ensures that the drug substance is available in higher concentrations than oral administration. As the population ages, ophthalmic solutions are increasingly in demand. Recently there has been success of a number of drugs, both utilizing NCEs and previously approved APIs for alternate indications, to treat ocular diseases which has resulted in an increased interest in ocular drug discovery.<\/p><p>Bora\u2019s Taoyuan facility, the first FDA-approved ophthalmic site in Taiwan, further strengthens Bora\u2019s position as a global CDMO leader. The facility established in 2014, specializes in sterile ophthalmic products and can produce all the main sterile ophthalmic forms, such as, multi-dose with preservatives, multi-dose without preservatives, gels, creams, and ointments.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-f80f872 e-flex e-con-boxed e-con e-parent\" data-id=\"f80f872\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;gradient&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-80acb7d elementor-widget elementor-widget-heading\" data-id=\"80acb7d\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Bora Taoyuan has the track record of success and is the ideal manufacturing partner for your ophthalmic products<\/h2>\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-959601d e-con-full e-flex e-con e-child\" data-id=\"959601d\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-b10ffb4 e-con-full e-flex e-con e-child\" data-id=\"b10ffb4\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-e8dbe19 elementor-widget elementor-widget-image\" data-id=\"e8dbe19\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"679\" height=\"492\" src=\"https:\/\/boracdmo.com\/wp-content\/uploads\/sites\/2\/2023\/02\/ophthalmic-eye-abstract.png\" class=\"attachment-large size-large wp-image-248014\" alt=\"\" srcset=\"https:\/\/boracdmo.com\/wp-content\/uploads\/sites\/2\/2023\/02\/ophthalmic-eye-abstract.png 679w, https:\/\/boracdmo.com\/wp-content\/uploads\/sites\/2\/2023\/02\/ophthalmic-eye-abstract-300x217.png 300w, https:\/\/boracdmo.com\/wp-content\/uploads\/sites\/2\/2023\/02\/ophthalmic-eye-abstract-480x348.png 480w\" sizes=\"(max-width: 679px) 100vw, 679px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-170fc49 e-con-full e-flex e-con e-child\" data-id=\"170fc49\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-636c233 elementor-widget elementor-widget-text-editor\" data-id=\"636c233\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<div class=\"et_pb_module et_pb_text et_pb_text_4 bullet-list et_pb_text_align_left et_pb_bg_layout_light\"><div class=\"et_pb_text_inner\"><p>\u200bThe eye has special attributes that allow local drug delivery and at Bora, superior quality is our prime directive as we manufacture products that meet the high sterility requirement for ophthalmic use. As a leader in ophthalmic manufacturing, Bora provides innovation and rigorous quality standards for each product.<\/p><p>Among the liquid dosage forms, we manufacture products in solution, suspension, nano-suspension, and nano-emulsion. Among the semi-solid dosage forms, we have abilities to manufacture gel, cream, and ointment products.<\/p><\/div><\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-4070299 blur elementor-widget elementor-widget-button\" data-id=\"4070299\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t\t\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"https:\/\/boracdmo.com\/contact-us\/\" data-cta=\"true\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t<span class=\"elementor-button-icon\">\n\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-arrow-right\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M190.5 66.9l22.2-22.2c9.4-9.4 24.6-9.4 33.9 0L441 239c9.4 9.4 9.4 24.6 0 33.9L246.6 467.3c-9.4 9.4-24.6 9.4-33.9 0l-22.2-22.2c-9.5-9.5-9.3-25 .4-34.3L311.4 296H24c-13.3 0-24-10.7-24-24v-32c0-13.3 10.7-24 24-24h287.4L190.9 101.2c-9.8-9.3-10-24.8-.4-34.3z\"><\/path><\/svg>\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">Contact a Bora Expert<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-914600d e-flex e-con-boxed e-con e-parent\" data-id=\"914600d\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-8ea3214 e-con-full e-flex e-con e-child\" data-id=\"8ea3214\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-d806216 e-con-full card e-flex e-con e-child\" data-id=\"d806216\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-40321eb elementor-widget elementor-widget-heading\" data-id=\"40321eb\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Nano-emulsions and nano-solutions are considered some of the most promising routes of delivery of ophthalmic drugs<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-8b1a048 elementor-widget elementor-widget-text-editor\" data-id=\"8b1a048\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<div class=\"et_pb_module et_pb_text et_pb_text_6 bullet-list et_pb_text_align_left et_pb_bg_layout_light\"><div class=\"et_pb_text_inner\"><p>These novel approaches emphasize on the benefits of various ocular drug delivery systems, for example, eye ointments, gels and use of viscosity enhancers, prodrugs, penetration enhancers, microparticles, liposomes, nanoparticles, nanosuspension, and micro-emulsion. In addition to acting as a carrier to deliver poorly water soluble API and reducing the oxidative degradation of API, ointment products can cover the wound for postoperative patients and prolong the protection and release of the API.<\/p><\/div><\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-623a735 elementor-icon-list--layout-traditional elementor-list-item-link-full_width elementor-widget elementor-widget-icon-list\" data-id=\"623a735\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"icon-list.default\">\n\t\t\t\t\t\t\t<ul class=\"elementor-icon-list-items\">\n\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-square-full\" viewBox=\"0 0 512 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M512 512H0V0h512v512z\"><\/path><\/svg>\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">Administration of poorly water soluble API<\/span>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-square-full\" viewBox=\"0 0 512 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M512 512H0V0h512v512z\"><\/path><\/svg>\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">Increased bioavailability<\/span>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-square-full\" viewBox=\"0 0 512 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M512 512H0V0h512v512z\"><\/path><\/svg>\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">Improved stability<\/span>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-square-full\" viewBox=\"0 0 512 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M512 512H0V0h512v512z\"><\/path><\/svg>\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">Topical ocular extended\/controlled release<\/span>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-square-full\" viewBox=\"0 0 512 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M512 512H0V0h512v512z\"><\/path><\/svg>\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">Reduced side effect of API<\/span>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t<\/ul>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-3ff089a e-con-full e-flex e-con e-child\" data-id=\"3ff089a\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-79c1464 elementor-widget elementor-widget-image\" data-id=\"79c1464\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"800\" height=\"600\" src=\"https:\/\/boracdmo.com\/wp-content\/uploads\/sites\/2\/2023\/02\/FlexiFill-Opthalmics.jpg\" class=\"attachment-large size-large wp-image-248019\" alt=\"FlexiFill F940 ophthalmic filling system operating inside a sterile pharmaceutical cleanroom facility.\" srcset=\"https:\/\/boracdmo.com\/wp-content\/uploads\/sites\/2\/2023\/02\/FlexiFill-Opthalmics.jpg 1024w, https:\/\/boracdmo.com\/wp-content\/uploads\/sites\/2\/2023\/02\/FlexiFill-Opthalmics-300x225.jpg 300w, https:\/\/boracdmo.com\/wp-content\/uploads\/sites\/2\/2023\/02\/FlexiFill-Opthalmics-768x576.jpg 768w, https:\/\/boracdmo.com\/wp-content\/uploads\/sites\/2\/2023\/02\/FlexiFill-Opthalmics-510x382.jpg 510w, https:\/\/boracdmo.com\/wp-content\/uploads\/sites\/2\/2023\/02\/FlexiFill-Opthalmics-980x735.jpg 980w, https:\/\/boracdmo.com\/wp-content\/uploads\/sites\/2\/2023\/02\/FlexiFill-Opthalmics-480x360.jpg 480w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-e158f21 e-flex e-con-boxed e-con e-parent\" data-id=\"e158f21\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;gradient&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-27711ef e-con-full e-flex e-con e-child\" data-id=\"27711ef\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-77028b6 elementor-invisible elementor-widget elementor-widget-video\" data-id=\"77028b6\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;video_type&quot;:&quot;hosted&quot;,&quot;_animation&quot;:&quot;fadeIn&quot;,&quot;controls&quot;:&quot;yes&quot;}\" data-widget_type=\"video.default\">\n\t\t\t\t\t\t\t<div class=\"e-hosted-video elementor-wrapper elementor-open-inline\">\n\t\t\t\t\t<video class=\"elementor-video\" src=\"https:\/\/boracdmo.com\/wp-content\/uploads\/sites\/2\/2023\/02\/IMA-Demo-1.mp4\" controls=\"\" preload=\"metadata\" controlsList=\"nodownload\"><\/video>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-2ad6a4f e-con-full e-flex e-con e-child\" data-id=\"2ad6a4f\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-b69195d elementor-widget elementor-widget-heading\" data-id=\"b69195d\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">State-of-the-art manufacturing, filling, packaging, and serialization<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-1b0a4b0 elementor-widget elementor-widget-text-editor\" data-id=\"1b0a4b0\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>At our Taoyuan ophthalmic manufacturing facility, customers\u2019 products are manufactured in a controlled environment (ISO 5 for filling operation) that minimizes contact with airborne contaminants. Our customized suites include one-way air flow, high-efficiency particulate air (HEPA) filters, isolators\/ restricted access barrier systems (RABS), automated handling systems operated by trained and experienced staff. The automated handling system incorporates the aseptic operations from filling, nozzle insertion, and capping, and the packaging operations for labeling and encasing. Bora currently fills liquid form products from 2.5 mL to 15 mL in different sizes and shapes of eye-drop bottles. Among the semi-solid dosage form, we are able to produce ointment, cream and gel products and fill 1 gm to 5 gm in different sizes of aluminum or laminated tubes. Ophthalmic products require the primary and secondary packaging to be completed and inspected with the same care as the manufacturing of the product itself.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Commercial ophthalmic manufacturing \u200bThe known advantages of the ocular route of drug administration is that it ensures that the drug substance is available in higher concentrations than oral administration. As the population ages, ophthalmic solutions are increasingly in demand. Recently there has been success of a number of drugs, both utilizing NCEs and previously approved [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"parent":0,"menu_order":2,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"content-type":"","_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"class_list":["post-248468","page","type-page","status-publish","hentry"],"aioseo_notices":[],"acf":[],"_links":{"self":[{"href":"https:\/\/boracdmo.com\/en\/wp-json\/wp\/v2\/pages\/248468","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/boracdmo.com\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/boracdmo.com\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/boracdmo.com\/en\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/boracdmo.com\/en\/wp-json\/wp\/v2\/comments?post=248468"}],"version-history":[{"count":53,"href":"https:\/\/boracdmo.com\/en\/wp-json\/wp\/v2\/pages\/248468\/revisions"}],"predecessor-version":[{"id":987502795,"href":"https:\/\/boracdmo.com\/en\/wp-json\/wp\/v2\/pages\/248468\/revisions\/987502795"}],"wp:attachment":[{"href":"https:\/\/boracdmo.com\/en\/wp-json\/wp\/v2\/media?parent=248468"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}